Work

Author response: Translation attenuation by minocycline enhances longevity and proteostasis in old post-stress-responsive organisms

Year: 2018

Type: peer-review

Abstract: Directly targeting the ribosome to attenuate translation partly mimics the integrated stress response, increasing lifespan and preserving protein folding capacity even in older individuals with dysfunctional stress response signaling.

DOI: 10.7554/elife.40314.023

Authors: Gregory M Solis, Rozina Kardakaris, Elizabeth R Valentine, Liron Bar-Peled, Alice L Chen, Megan M Blewett, Mark A McCormick, James R Williamson, Brian Kennedy, Benjamin F Cravatt, Michael Petrascheck

Institutions: Scripps Research Institute, Buck Institute for Research on Aging

Language: English

Topic: Genetics, Aging, and Longevity in Model Organisms

Subfield: Aging

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W2988869585

Cites:

Cited by: 1

Related to: 10