Work

Author response: Defective apical extrusion signaling contributes to aggressive tumor hallmarks

Year: 2014

Type: peer-review

Abstract: Disrupting extrusion, a process that drives epithelial cell death, leads to increased cell survival, poor barrier function, and enhanced cell invasion and, thereby, promotes tumor initiation and progression.

DOI: 10.7554/elife.04069.015

Authors: Yapeng Gu, Jill Shea, Gloria Slattum, Matthew A Firpo, Margaret Alexander, Sean J Mulvihill, Vita M Golubovskaya, Jody Rosenblatt

Institutions: Huntsman Cancer Institute, University of Utah, Roswell Park Comprehensive Cancer Center

Language: English

Topic: Cell death mechanisms and regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W2989536843

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