Work

Author response: Dissecting the sharp response of a canonical developmental enhancer reveals multiple sources of cooperativity

Year: 2019

Type: peer-review

Abstract: The sharp expression pattern driven by a classic, simple animal enhancer is determined by multiple molecular mechanisms, not only cooperative binding of the activating transcription factor as was previously thought.

DOI: 10.7554/elife.41266.026

Authors: Jeehae Park, Javier Estrada, Gemma Johnson, Ben J Vincent, Chiara Ricci-Tam, Meghan DJ Bragdon, Yekaterina Shulgina, Anna Cha, Zeba Wunderlich, Jeremy Gunawardena, Angela H DePace

Institutions: Harvard University, Center for Systems Biology

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

OpenAlex ID: W2989547652

Cites:

Cited by: 2

Related to: 10