An Approach to the Pharmacotherapy of Neuroleptic Malignant Syndrome
Year: 2025
Type: article
Study design: Case Report
Abstract: Neuroleptic malignant syndrome is a rare, idiosyncratic emergency associated with exposure to dopamine antagonists, commonly antipsychotic drugs. The typical clinical picture consists of altered consciousness, muscular rigidity, fever, and autonomic instability. While the condition has generally been well described, the pathophysiology is still poorly understood. The importance of this case report is to highlight the lack of robust evidence-based treatment for this emergency. We submit an approach to the pharmacotherapy of neuroleptic malignant syndrome based on the available evidence.
Source: Psychopharmacology Bulletin
DOI: 10.64719/pb.4581
Authors: Roland van Rensburg, Eric H. Decloedt
Institution: Stellenbosch University
Language: English
Subfield: Psychiatry and Mental health
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2990514516