Get started
Work

Determinants of Viral Resuppression or Persistent Virologic Failure After Initial Failure With Second-Line Antiretroviral Treatment Among Asian Children and Adolescents With HIV

Year: 2019
Type: article
Study design: Observational Study
Abstract: Of 56 children with perinatally acquired human immunodeficiency virus (HIV) who had been prescribed second-line protease inhibitor-based antiretroviral therapy and had ≥1 previous episode of viral failure (HIV RNA, ≥1000 copies/mL), 46% had ≥1, 34% had ≥2, and 23% had ≥3 consecutive episodes of viral failure during the 2 years of follow-up. Two of these children experienced a major protease inhibitor mutation.
DOI: 10.1093/jpids/piz034
Authors: Sirinya Teeraananchai, Stephen J Kerr, Monica Gandhi, Viet Chau Do, Lam Van Nguyen, Dan Ngoc Hanh Tran, Pope Kosalaraksa, Thida Singtoroj, Narukjaporn Thammajaruk, Thidarat Jupimai, Annette H Sohn
Institutions: HIV Netherlands Australia Thailand Research Collaboration, Chulalongkorn University, San Francisco General Hospital, University of California, San Francisco, Children's Hospital 2, Vietnam National Children's Hospital, Children's Hospital 1, Khon Kaen University, American Foundation for AIDS Research
Language: English
Field: Medicine
Open Access status: green
Funders: amfAR, The Foundation for AIDS Research, ViiV Healthcare, National Institutes of Health, National Institute of Allergy and Infectious Diseases, National Institute of Child Health and Human Development, Eunice Kennedy Shriver National Institute of Child Health and Human Development
OpenAlex ID: W2990954381
FWCI: 0.514
Cites: 9
Cited by: 5
Related to: 10