Work

MicroRNAs as Biomarkers for Psychiatric Conditions: A Review of Current Research.

Year: 2017

Type: article

Abstract: Neural-derived exosomes can be used as diagnostic markers to screen for various psychiatric conditions. These intravenously injected exosomes carry the potential to cross the blood brain barrier and deliver miRNA molecules specifically to neurons, microglia, and oligodendrocytes in the brain, resulting in specific gene knockdown. Here the authors review and discuss the current research on microRNA molecules and the therapeutic roles they may potentially play in treating depression, bipolar disorder, and schizophrenia.

Source: PubMed Central

Authors: Anoop Narahari, Mariyah Hussain, Venkatesh Sreeram

Institutions: University of Alabama, University of Alabama at Birmingham

Language: English

Topic: Extracellular vesicles in disease

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2991116638

FWCI: 2.678

Cites: 15

Cited by: 47

Related to: 10