Estimating Change in Tremor Amplitude Using Clinical Ratings: Recommendations for Clinical Trials
Year: 2018
Type: article
Abstract: refer to the initial and final values. For a 0-4 scale and α = 0.5, a 1-point reduction in tremor ratings is roughly a 68% reduction in tremor amplitude, regardless of the baseline tremor rating (e.g., 2 or 4). Similarly, a 2-point reduction is roughly a 90% reduction in tremor amplitude. These Weber-Fechner equations should be used in clinical trials for computing and interpreting change in tremor, assessed with clinical ratings.
Source: PubMed Central
DOI: 10.7916/d89c8f3c
Author: Elble, Rodger J
Institutions: SIU Medicine, Yale University
Language: English
Topic: Motor Control and Adaptation
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2991141062