Work

Triptolide protects podocytes from TGF-β-induced injury by preventing miR-30 downregulation.

Year: 2017

Type: article

Abstract: study and found that Triptolide prevented TGF-β-induced miR-30 downregulation and Smad2/3 phosphorylation in the isolated glomeruli of mice or rats. Thus, our study has provided novel insights into the mechanism underlying the therapeutic effectiveness of Triptolide on podocytopathies.

Source: Europe PMC (PubMed Central)

Authors: Qianqian Yang, Mengjie Sun, Ying Chen, Yuqiu Lu, Yuting Ye, Hui Song, Xiaodong Xu, Shaolin Shi, Jinquan Wang

Institutions: Nanjing General Hospital of Nanjing Military Command, Nanjing University

Language: English

Topic: Natural Compounds in Disease Treatment

Subfield: Complementary and alternative medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W2991519018

FWCI: 3.558

Cites: 43

Cited by: 13

Related to: 10