Dynamic patterns of H3K4me3, H3K27me3, and Nanog during rabbit embryo development.
Year: 2019
Type: article
Abstract: < 0.05). The observed decrease in H3K4me3 and increase in H3K27me3 as development progressed in preimplantation rabbit embryos, together with late Nanog expression, indicates a correlation of these factors with early embryonic cell fate determination and differentiation. Our study provides a specific and dynamic profile of histone modifications and gene expression that will be important for the derivation of rabbit embryonic stem cells and improving rabbit cloning by somatic cell nuclear transfer.
Source: Europe PMC (PubMed Central)
Institution: Nanjing Normal University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2992130567