Anti-inflammatory, Analgesic and Anti - Pyretic Activity of Cassava Leaves Extract
Year: 2013
Type: article
Abstract: Objective: The objective of this study was to evaluate the in-vivo anti-inflammatory, anti- pyretic, analgesic activities and phytochemical analysis of ethanol cassava leaf extract (ECLE). Material and method: The leaf extract was prepared with ethanol filter and rotary evaporated and stored in desiccator. Preliminary phytochemical screening terpernoids, tannins, flavonoids, anthraquinones, alkaloids, and cardiac glycosides and carotenoids were carried out. A different concentration (100,250,500mg/kg) of the leaf extract was evaluated for their anti-inflammary, analgesic and anti-pyretic effect using carrageenan and histamine induced oedema, acetic acid induced writhing and yeast induced pyrexia in rats respectively. Result and Conclusion: The extract at concentration100, 250,500mg/kg was able to inhibit carrageenan and histamine induced oedema, acetic acid induced writhing and yeast induced pyrexia in rats. Terpernoids, tannins, flavonoids, carotenoids were found present in the ECLE.
Institution: UCSI University
Language: English
Topic: Medicinal Plant Research
Subfield: Plant Science
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W2992369628