Therapeutic management and comorbidities in opiate-dependent patients undergoing a replacement therapy programme in Spain: the PROTEUS study
Year: 2011
Type: article
Study design: Observational Study
Abstract: The aim of this study was to comprehensively describe the clinical comorbidities, concomitant treatments and the current therapeutic management of opiate-dependent patients undergoing a replacement therapy programme (RTP).This is an observational, cross-sectional, multicentre, epidemiological study conducted in 74 healthcare centres for drug users.Patients were diagnosed with Opiate Dependence (OD), and enrolled in a RTP in Spain (N=624).Most patients were men (84%); they received methadone (94%) at a mean dose of 61.52mg/day during the maintenance phase, orally (95%) with take-home doses (76%).High rates of infectious (59%) and psychiatric comorbidities (67%) were found.Patients infected by HIV, HCV or coinfected by HIV/HCV were given signiicantly higher methadone doses (p<0.0001).
Institution: University of Edinburgh
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W2994274865