Work

Structure–Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties

Year: 2019

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.9b01815

Authors: Hao Chen, Shanshan Deng, Yuxi Wang, Najah Albadari, Gyanendra Kumar, Dejian Ma, Weimin Li, Stephen W. White, Duane D. Miller, Wei Li

Institutions: University of Tennessee Health Science Center, Sichuan University, West China Hospital of Sichuan University, St. Jude Children's Research Hospital

Language: English

Topic: Heterocyclic Compound Synthesis and Bioactivity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: University of Tennessee, Office of the Director, National Cancer Institute, National Center for Research Resources

Awards: Acquisition of a 400MHz Solution NMR System with an Autosampler, G8493048019, G8693434331, Targeting the colchicine binding site in tubulin for cancer therapy

OpenAlex ID: W2994636819

FWCI: 2.577

Cites: 39

Cited by: 46

Related to: 10