Work

LJ000328, a novel ALK2/3 kinase inhibitor, represses hepcidin and significantly improves the phenotype of IRIDA

Year: 2019

Type: article

Abstract: LJ000328, a novel ALK2/3 kinase inhibitor, represses hepcidin and significantly improves the phenotype of IRIDA

Source: Haematologica

DOI: 10.3324/haematol.2019.236133

Authors: Audrey Belot, Ophélie Gourbeyre, Alexis Fay, Anais Palin, Céline Besson-Fournier, Chloé Latour, Corey R. Hopkins, George F. Tidmarsh, Hélène Coppin, Marie-Paule Roth, Matthew R. Ritter, Charles C. Hong, Delphine Meynard

Institutions: Université Toulouse III - Paul Sabatier, Inserm, École Nationale Vétérinaire de Toulouse, Institut de Recherche en Santé Digestive, Université de Toulouse, University of Nebraska Medical Center, La Jolla Pharmaceutical (United States), University of Maryland, Baltimore, University of Maryland School of Medicine

Language: English

Topic: Iron Metabolism and Disorders

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $379

Funders: Cooley's Anemia Foundation, Fondation Maladies Rares, Agence Nationale de la Recherche, Institut National de la Santé et de la Recherche Médicale, Universidad de Oviedo, Conseil Régional Midi-Pyrénées

Awards: Restriction of iron availability to pathogens: mechanisms and contribution to the host antimicrobial defense, Role of iron in the pathogenesis of NASH, G6803667113, Targeting Matriptase-2 to develop new therapeutic strategies for iron related disorders, Equipements plateforme animalerie infectieuse de haute-sécurité de Midi Pyrénées

OpenAlex ID: W2995493794

FWCI: 2.293

Cites: 17

Cited by: 19

Related to: 10