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Liver‐on‐a‐Chip: In Vitro Human Liver Model of Nonalcoholic Steatohepatitis by Coculturing Hepatocytes, Endothelial Cells, and Kupffer Cells (Adv. Healthcare Mater. 24/2019)

Year: 2019

Type: article

Abstract: In article number 1901379, Junmin Lee, Ali Khademhosseini, and co-workers, develop an in vitro human liver model of non-alcoholic fatty liver disease (NAFLD) by co-culturing human hepatocytes, umbilical vein endothelial cells (HUVECs), and Kupffer cells (KCs) into spheroids. The proposed system is an appropriate model to mimic and monitor the progression of NAFLD from steatosis into steatohepatitis.

Source: Advanced Healthcare Materials

DOI: 10.1002/adhm.201970094

Authors: Ceri‐Anne E. Suurmond, Soufian Lasli, Floor W. van den Dolder, Aly Ung, Han‐Jun Kim, Praveen Bandaru, KangJu Lee, Hyun‐Jong Cho, Samad Ahadian, Nureddin Ashammakhi, Mehmet R. Dokmeci, Junmin Lee, Ali Khademhosseini

Institutions: University of California, Los Angeles, University of Twente, École Polytechnique Fédérale de Lausanne, University Medical Center Utrecht, Kangwon National University

Language: English

Topic: 3D Printing in Biomedical Research

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2995613288

FWCI: 0.176

Cites:

Cited by: 2

Related to: 10