Work

Translating exercise benefits in sickle cell disease

Year: 2019

Type: article

Abstract: The pathophysiologic basis for reduced fitness in sickle cell disease (SCD) is multifactorial and characterized by impaired oxygen-carrying capacity, derangements in the cardiopulmonary response to exercise, and abnormal metabolic responses in working muscles. In this issue of Blood, Merlet et al demonstrated in a provocative and elegant study that exercise training led to muscle capillary growth in people with SCD.

Source: Blood

DOI: 10.1182/blood.2019003651

Authors: Dan M. Cooper, Robert I. Liem

Institution: Lurie Children's Hospital

Language: English

Topic: Hemoglobinopathies and Related Disorders

Subfield: Genetics (clinical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Heart, Lung, and Blood Institute