Year: 2020
Type: article
Abstract: BACKGROUND: In Europe cardiovascular disease (CVD) is responsible for 3.9 million deaths (45% of deaths), being ischaemic heart disease, stroke, hypertension (leading to heart failure) the major cause of these CVD related deaths. Periodontitis is also a chronic non-communicable disease (NCD) with a high prevalence, being severe periodontitis, affecting 11.2% of the world's population, the sixth most common human disease. MATERIAL AND METHODS: There is now a significant body of evidence to support independent associations between severe periodontitis and several NCDs, in particular CVD. In 2012 a joint workshop was held between the European Federation of Periodontology (EFP) and the American Academy of Periodontology to review the literature relating periodontitis and systemic diseases, including CVD. In the last five years important new scientific information has emerged providing important emerging evidence to support these associations RESULTS AND CONCLUSIONS: The present review reports the proceedings of the workshop jointly organised by the EFP and the World Heart Federation (WHF), which has updated the existing epidemiological evidence for significant associations between periodontitis and CVD, the mechanistic links and the impact of periodontal therapy on cardiovascular and surrogate outcomes. This review has also focused on the potential risk and complications of periodontal therapy in patients on anti thrombotic therapy and has made recommendations for dentists, physicians and for patients visiting both the dental and medical practices.
DOI: 10.1111/jcpe.13189
Authors: Mariano Sanz, Alvaro Marco del Castillo, Søren Jepsen, Jose R. Gonzalez‐Juanatey, Francesco D’Aiuto, Philippe Bouchard, Iain Chapple, Thomas Dietrich, Israel Gotsman, Filippo Graziani, David Herrera, Bruno Loos, Phoebus Madianos, Jean‐Baptiste Michel, Pablo Perel, Burkert Pieske, Lior Shapira, Michael Shechter, Maurizio Tonetti, Charalambos Vlachopoulos, Gernot Wimmer
Institutions: Universidad Complutense de Madrid, Hospital Universitario Ramón y Cajal, University of Bonn, Universidade de Santiago de Compostela, Centro de Investigación en Red en Enfermedades Cardiovasculares, Instituto de Investigación Sanitaria de Santiago, Eastman Dental Hospital, University College London, Hôpital Rothschild, Université Paris Diderot, University of Birmingham, Hadassah Medical Center, University of Pisa, Academic Center for Dentistry Amsterdam, National and Kapodistrian University of Athens, Inserm, Laboratoire de Recherche Vasculaire Translationnelle, Hôpital Bichat-Claude-Bernard, London School of Hygiene & Tropical Medicine, World Heart Federation, German Centre for Cardiovascular Research, Charité – Universitätsmedizin Berlin, Hebrew University of Jerusalem, Tel Aviv University, Sheba Medical Center, Prince Philip Dental Hospital, University of Hong Kong, University of Graz
Language: English
Subfield: Periodontics
Field: Dentistry
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $4,300
OpenAlex ID: W2995886183