Work

Roles of HIF1 and HIF2 in pulmonary hypertension: it all depends on the context

Year: 2019

Type: editorial

Abstract: HIF1 and HIF2 can play complementary, opposing or unrelated roles in mediating the response to low oxygen levels in different cell types. This study shows HIF2 plays a dominant role in mediating the development of PH in response to environmental hypoxia.http://bit.ly/2Cy46sR

Source: European Respiratory Journal

DOI: 10.1183/13993003.01929-2019

Authors: Gregory B. Waypa, Paul T. Schumacker

Institutions: Northwestern University, Lurie Children's Hospital

Language: English

Topic: Pulmonary Hypertension Research and Treatments

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Heart, Lung, and Blood Institute