Work

The Staphylococcus aureus IsdH Receptor Forms a Dynamic Complex with Human Hemoglobin that Triggers Heme Release via Two Distinct Hot Spots

Year: 2019

Type: article

Source: Journal of Molecular Biology

DOI: 10.1016/j.jmb.2019.12.023

Authors: Ken Ellis-Guardiola, Joseph Clayton, Clarissa Pham, Brendan J. Mahoney, Jeff Wereszczynski, Robert T. Clubb

Institutions: University of California, Los Angeles, Illinois Institute of Technology

Language: English

Topic: Hemoglobin structure and function

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Science Foundation, Foundation for the National Institutes of Health, National Institutes of Health, University of California, San Diego, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: G3307809370, G3405046010, G4719972967, G6995306467, Stopped-Flow Spectrometer, Development of a cell-based assay to discover new bacterial anti-infective agents, Molecular basis of heme scavenging by Gram-positive bacteria, Cell Surface Polymer Display in Gram-Positive Bacteria, Probing the Structure/Function/Dynamics Relationship in Biomolecular Complexes with Multiscale Computational Techniques

OpenAlex ID: W2996966858

FWCI: 0.887

Cites: 69

Cited by: 23

Related to: 10