Work

Genetic Determinants of Trehalose Utilization Are Not Associated With Severe Clostridium difficile Infection Outcome

Year: 2020

Type: article

Abstract: ABSTRACT In a case-control study of patients with C. difficile infection we found no statistically significant association between the presence of trehalose utilization variants in infecting C. difficile strains and development of severe infection. These results do not support trehalose utilization conferring enhanced virulence in the context of human C. difficile infections.

Source: Open Forum Infectious Diseases

DOI: 10.1093/ofid/ofz548

Authors: Katie Saund, Krishna Rao, Vincent B Young, Evan S Snitkin

Institutions: University of Michigan, Michigan Medicine

Language: English

Topic: Clostridium difficile and Clostridium perfringens research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,053