Work

The role of medical gas in stroke: an updated review

Year: 2019

Type: article

Abstract: Medical gas is a large class of bioactive gases used in clinical medicine and basic scientific research. At present, the role of medical gas in neuroprotection has received growing attention. Stroke is a leading cause of death and disability in adults worldwide, but current treatment is still very limited. The common pathological changes of these two types of stroke may include excitotoxicity, free radical release, inflammation, cell death, mitochondrial disorder, and blood-brain barrier disruption. In this review, we will discuss the pathological mechanisms of stroke and the role of two medical gases (hydrogen and hydrogen sulfide) in stroke, which may potentially provide a new insight into the treatment of stroke.

Source: Medical Gas Research

DOI: 10.4103/2045-9912.273960

Authors: Sheng Chen, Ze-Yu Zhang, Yuan-Jian Fang, Yu-Jie Luo, Cameron Lenahan, Jian-Ming Zhang

Institutions: Second Affiliated Hospital of Zhejiang University, Zhejiang University, Loma Linda University, Burrell College of Osteopathic Medicine

Language: English

Topic: Hydrogen's biological and therapeutic effects

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Natural Science Foundation of China, Fundamental Research Funds for the Central Universities