New developments in the field of mastocytosis and mast cell activation syndromes: a summary of the Annual Meeting of the European Competence Network on Mastocytosis (ECNM) 2019
Year: 2019
Type: article
Abstract: Mastocytosis are a group of hematologic neoplasms characterized by an accumulation of atypical mast cells in one or several organs/tissues, often accompanied by mast cell activation. Whereas in children the disease manifestations are mostly limited to the skin, in adults the disease is usually systemic (systemic mastocytosis; SM) and involves the bone marrow and/or other internal organs. Several variants of SM have been defined. Whereas most patients have indolent SM, some patients have advanced SM, which underlines the complexity of SM. In 2002, a European consortium of clinicians and scientists initiated a multidisciplinary, multi-national cooperative network, termed the 'European Competence Network on Mastocytosis' (ECNM), with the aim to improve diagnosis and therapy of patients with mastocytosis and other mast cell activation disorders. Since then, members of the ECNM have organized Annual Meetings in several European countries. The present article provides a summary of advances in the field presented during the 17th Annual ECNM meeting held in Salzburg in October 2019.
Institutions: Inserm, Centre de Recherche des Cordeliers, Pitié-Salpêtrière Hospital, Paracelsus Medical University, Stanford Medicine, Stanford Cancer Institute, Stanford University, Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, University of Basel, University Hospital of Basel, Virginia Commonwealth University, Virginia Commonwealth University Medical Center, University of Michigan, Pathologisches Institut, Ludwig-Maximilians-Universität München
Language: English
Topic: Mast cells and histamine
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2998386678