Work

After-Death Functions of Cell Death.

Year: 2019

Type: article

Abstract: Cell death can occur through numerous regulated mechanisms, from apoptosis to necrosis, entosis, and others. Each has a distinct mode of regulation and effect on tissue homeostasis. While the elimination of individual cells is typically considered the relevant physiologic endpoint of cell death, in some cases the remnants left behind by death can also function to support tissue homeostasis. Here we discuss specific functions of the end products of cell death, and how "after-death" functions may contribute to the roles of programmed cell death in physiology.

Source: Europe PMC (PubMed Central)

Authors: Yongchan Lee, Michael Overholtzer

Institutions: Memorial Sloan Kettering Cancer Center, Cornell University, Weill Cornell Medicine, Louis V. Gerstner, Jr. Graduate School of Biomedical Sciences

Language: English

Topic: Cell death mechanisms and regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Cancer Institute

Awards: The role of entosis in human cancers, Cancer Center Support Grant

OpenAlex ID: W2998641455

FWCI: 0.579

Cites: 78

Cited by: 9

Related to: 10