Work

Synthesis, mechanisms of action, and toxicity of novel aminophosphonates derivatives conjugated irinotecan in vitro and in vivo as potent antitumor agents

Year: 2020

Type: article

Source: European Journal of Medicinal Chemistry

DOI: 10.1016/j.ejmech.2020.112067

Authors: Xiaochao Huang, Meng Wang, Qinghong You, Jing Kong, Haijiang Zhang, Chunhao Yu, Yanming Wang, Hengshan Wang, Rizhen Huang

Institutions: Guilin Medical University, Guangxi Normal University, Huai'an University, State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, Jiangsu Key Laboratory of Regional Resource Exploitation and Medicinal Research

Language: English

Topic: Organophosphorus compounds synthesis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, Ministry of Education of the People's Republic of China, Natural Science Foundation of Guangxi Province, Natural Science Foundation of Jiangsu Province, Jiangsu Provincial Key Research and Development Program, Key University Science Research Project of Jiangsu Province, Jiangsu Key Laboratory of Regional Resource Exploitation and Medicinal Research

Awards: G2285221494, G244117186, G3438765607, G5033277126, G5245509347, G6891006456, G7653996564, G7851701701, 卷柏属瑶药中新型PDE4 / MMPs双靶点抑制剂的协同抗肿瘤耐药机制, 源于紫堇属瑶药的非温敏型生物碱类TRPV1调节剂的发现与结构优化及特异机制研究

OpenAlex ID: W2999004841

FWCI: 1.45

Cites: 45

Cited by: 30

Related to: 10