Work

Correlation of Linezolid Hair Concentrations with Plasma Exposure in Patients with Drug-Resistant Tuberculosis

Year: 2020

Type: article

Abstract: Plasma drug quantification has a potential role as a biomarker of tuberculosis (TB) treatment adherence, but the utility of short-half-life drugs such as linezolid (1) for adherence monitoring may be limited due to rapid plasma clearance and inability to capture long-term dosing.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.02145-19

Authors: Sean Wasserman, Shu Huo, Karina Ky, Ysabella Noelle Malig, Ali Esmail, Keertan Dheda, Peter Bacchetti, Roy Gerona, Gary Maartens, Monica Gandhi, John Metcalfe

Institutions: University of Cape Town, Wellcome Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, San Francisco General Hospital, University of California, San Francisco, London School of Hygiene & Tropical Medicine

Language: English

Topic: Tuberculosis Research and Epidemiology

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Wellcome Trust, South African Medical Research Council, National Institutes of Health, National Institute of Mental Health, National Institute of Allergy and Infectious Diseases, Fogarty International Center, European and Developing Countries Clinical Trials Partnership

Awards: G1541260118, Centre for Infectious Diseases Research in Africa (CIDRI-Africa), Novel biomarkers predictive of susceptibility and treatment response in patients with MDR-TB, G5934716681, G6301998524, G6455515392, G7456479958, G81379742, G9000145151, G9000227907, Center for AIDS Prevention Studies (CAPS), G97119092

OpenAlex ID: W2999334682

FWCI: 0.06

Cites: 6

Cited by: 2

Related to: 10