Year: 2020
Type: conference-paper
Abstract: Introduction: Approximately 9.4% of the US population has diabetes, while about 85% of the US population consumes over a 100mg of caffeine daily.Whereas several epidemiological studies indicate that long-term coffee consumption reduces the risk of Type 2 diabetes mellitus (T2DM), the short-term effect of its consumption on glycemic control and diabetic complications warrants further elucidation.This is the focus of our research inquiry.Methods: The blood glucose levels of 21 healthy individuals were measured using a glucometer after a carbohydrate-rich meal.For the control trial, each individual's blood glucose levels was taken before the meal and then 15 mins, 45 mins, and 60 mins after eating the meal.For the experimental trial, each individual repeated the control trial but 30 mins after consuming caffeine.The meal was composed of a bagel, cream cheese, and a glucose drink.Results: There was a significant time-dependent change in blood glucose levels during the control trial, F(2.980, 59.602) = 21.492,p< 0.0005.There was a statistically significant increase in blood glucose levels with the caffeine trial -F(1, 20) = 5.830, p = 0.025.Conclusion: Caffeine consumption with or about meal time acutely impairs glucose tolerance by increasing the rate of spike of blood glucose levels, decreased insulin sensitivity and potentially increases the risk of β-cell dysfunction.In a diabetic patient, this effect could make a tight blood glucose control difficult to achieve therefore requiring higher doses of hypoglycemic drugs and increasing the risk of diabetic complications like diabetic retinopathy, neuropathy or ischemic heart disease.
Author: Ben Kalu
Language: English
Topic: Coffee research and impacts
Subfield: Pharmacology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W3000071379