Work

Histone H3 variants at the root of metastasis

Year: 2020

Type: article

Abstract: Chromatin remodeling is at the root of any cell fate decision, laying the foundation for the necessary reprogramming to occur. Our work shows histone H3 variants as a new addition to the ever-growing body of epigenetic regulators, one that is essential for cell fate transitions in carcinoma cells to promote tumor progression and metastasis.

Source: Molecular & Cellular Oncology

DOI: 10.1080/23723556.2019.1684128

Authors: Didem Ilter, John Blenis, Ana P. Gomes

Institution: Weill Cornell Medicine

Language: English

Topic: Genomics and Chromatin Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences