Work

Conjugated polymers as nanoparticle probes for fluorescence and photoacoustic imaging

Year: 2020

Type: review

Abstract: Bioimaging enables the visualisation of biological processes at the microscopic and macroscopic levels, finding applications from cellular tracking to whole body scanning for diagnosis purposes. The different techniques developed to acquire images make use of most radiation types of the electromagnetic spectrum. Recently, there has been interest in non-ionising radiation imaging techniques that can offer improved detection or additional information about biological processes, and fluorescence and photoacoustic imaging have become an eminent field. Conjugated polymers are versatile materials for bioimaging due to their tailored absorption and emission spectra and applications in both fluorescence and photoacoustic imaging. This review gives an overview on bioimaging techniques, with a special focus on conjugated polymer nanoparticles (CPNs), the different types of nanoparticle chemistries published and their preclinical safety assessment.

Source: Journal of Materials Chemistry B

DOI: 10.1039/c9tb02582k

Authors: Thais Fedatto Abelha, Cécile A. Dreiss, Mark A. Green, Lea Ann Dailey

Institutions: University of Nottingham, King's College London, University of Vienna

Language: English

Topic: Luminescence and Fluorescent Materials

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Engineering and Physical Sciences Research Council, Ciência sem Fronteiras