Work

mSphere of Influence: Synthetic Biology of Natural Product Biosynthesis

Year: 2020

Type: article

Abstract: Mark Walker studies the biosynthesis and engineering of bacterial natural products with the long-term goal of identifying new antibiotic compounds. In this mSphere of Influence, he reflects on how "Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A" by K. Yamanaka, K. A. Reynolds, R. D. Kersten, K. S. Ryan, et al. (Proc Natl Acad Sci USA 111:1957-1962, 2014, https://doi.org/10.1073/pnas.1319584111) impacted his thinking on using synthetic biology approaches to study natural product biosynthesis.

Source: mSphere

DOI: 10.1128/msphere.00954-19

Author: Mark C. Walker

Institution: University of New Mexico

Language: English

Topic: Microbial Natural Products and Biosynthesis

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

Open Access status: gold

Estimated APC paid: $3,500

OpenAlex ID: W3000744425

FWCI:

Cites: 7

Cited by:

Related to: 10