Year: 2020
Type: article
Abstract: In recent years, the endocannabinoid system has received great interest as a potential therapeutic target in numerous pathological conditions. Cannabinoids have shown an anticancer potential by modulating several pathways involved in cell growth, differentiation, migration, and angiogenesis. However, the therapeutic efficacy of cannabinoids is limited to the treatment of chemotherapy-induced symptoms or cancer pain, but their use as anticancer drugs in chemotherapeutic protocols requires further investigation. In this paper, we reviewed the role of cannabinoids in the modulation of signaling mechanisms implicated in tumor progression.
DOI: 10.3390/ijms21030747
Authors: Chiara Laezza, Cristina Pagano, Giovanna Navarra, Olga Pastorino, Maria Chiara Proto, Donatella Fiore, Chiara Piscopo, Patrizia Gazzerro, Maurizio Bifulco
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,112
Awards: G1878841690, G4749931472, G6483577402
OpenAlex ID: W3001018370