Work

Regioselective convergent synthesis of 2-arylidene thiazolo[3,2- a ]pyrimidines as potential anti-chikungunya agents

Year: 2020

Type: article

Abstract: Convergent and convenient regioselective synthesis of novel thiazolo[2,3- a ]pyrimidines was accomplished using the one-pot reaction of 6-ethylthiouracil, bromoacetic acid, anhydrous sodium acetate, acetic anhydride, acetic acid and suitable aldehyde.

Source: RSC Advances

DOI: 10.1039/d0ra00257g

Authors: Mohamed Fares, Patrick M. McCosker, Muhammad A. Alsherbiny, Anthony C. Willis, Timothy Clark, Johan Neyts, Dirk Jochmans, Paul A. Keller

Institutions: The University of Sydney, University of Wollongong, Illawarra Health and Medical Research Institute, Western Sydney University, Australian National University, Friedrich-Alexander-Universität Erlangen-Nürnberg, Rega Institute for Medical Research, KU Leuven

Language: English

Topic: Synthesis of heterocyclic compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042

Funder: University of Wollongong

OpenAlex ID: W3004401940

FWCI: 0.485

Cites: 30

Cited by: 9

Related to: 10