Work

Oncogenic ERG Represses PI3K Signaling through Downregulation of IRS2

Year: 2020

Type: article

Source: Cancer Research

DOI: 10.1158/0008-5472.can-19-1394

Authors: Ninghui Mao, Dong Gao, Wenhuo Hu, Sunyana Gadal, Haley Hieronymus, Shangqian Wang, Young Sun Lee, Patrick Sullivan, Zeda Zhang, Danielle Choi, Neal Rosen, Charles L. Sawyers, Anuradha Gopalan, Yu Chen, Brett S. Carver

Institution: Memorial Sloan Kettering Cancer Center

Language: English

Topic: Prostate Cancer Treatment and Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Howard Hughes Medical Institute, National Institutes of Health, National Cancer Institute

Awards: Understanding the role of an aberrant hepatic nuclear transcription circuit in prostate cancer tumorigenesis and castration resistance, G1845346269, The MSKCC-UW/Fred Hutch Prostate Cancer Drug Resistance and Sensitivity Center, Patient-Derived Models of Prostate Cancer for Personalized Medicine, Defining Response and Resistance to PI3K and AR inhibition in Prostate Cancer, G3239159112, Studies on oncoprotein-induced feedback: Basic and therapeutic implications, Understanding the roles of TMPRSS2 and ERG in pathogenesis of prostate cancer., Understanding Resistance to Next Generation Antiandrogens, Cancer Center Support Grant, SPORE in Prostate Cancer, Role of ETS factors in specifying prostate luminal cell identity and androgen receptor dependence

OpenAlex ID: W3004414444

FWCI: 1.125

Cites: 24

Cited by: 13

Related to: 10