Work

Automated access to well-defined ionic oligosaccharides

Year: 2020

Type: article

Abstract: Ionic polysaccharides are part of many biological events, but lack structural characterisation due to challenging purifications and complex synthesis. Four monosaccharides bearing modifications not found in nature are used for the automated synthesis of a collection of ionic oligosaccharides. Structural analysis reveals how the charge pattern affects glycan conformation.

Source: Organic & Biomolecular Chemistry

DOI: 10.1039/d0ob00137f

Authors: Yuntao Zhu, Theodore Tyrikos-Ergas, Kevin Schiefelbein, Andrea Grafmüller, Peter H. Seeberger, Martina Delbianco

Institution: Max Planck Institute of Colloids and Interfaces

Language: English

Topic: Carbohydrate Chemistry and Synthesis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Funder: Max-Planck-Gesellschaft

Awards: G6257920820, G829959894