Work

Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors

Year: 2020

Type: article

Source: Nature Biotechnology

DOI: 10.1038/s41587-020-0414-6

Authors: Jordan L. Doman, Aditya Raguram, Gregory A. Newby, David R. Liu

Institutions: Broad Institute, Howard Hughes Medical Institute, Harvard University

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: Howard Hughes Medical Institute, U.S. Department of Health and Human Services, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Human Genome Research Institute, National Cancer Institute, National Institute of General Medical Sciences, National Institute of Allergy and Infectious Diseases

Awards: Harvard Chemical Biology Graduate Program, G3186275704, Expanding the Scope of Base Editing, G4630203202, G6855349143, Cancer Center Support (Core) Grant, Integrating Chemistry and Evolution to Illuminate Biology and Enable Novel Therapeutics, Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease

OpenAlex ID: W3004494456

FWCI: 19.3

Cites: 59

Cited by: 478

Related to: 10