Work

Early TP53 alterations engage environmental exposures to promote gastric premalignancy in an integrative mouse model

Year: 2020

Type: article

Source: Nature Genetics

DOI: 10.1038/s41588-019-0574-9

Authors: Nilay S. Sethi, Osamu Kikuchi, Gina N. Duronio, Matthew D. Stachler, James M. McFarland, Ruben Ferrer-Luna, Yanxi Zhang, Chunyang Bao, Roderick Bronson, Deepa Patil, Francisco Sanchez-Vega, Jie-Bin Liu, Ewa Sicinska, Jean-Bernard Lazaro, Keith L. Ligon, Rameen Beroukhim, Adam J. Bass

Institutions: Broad Institute, Harvard University, Dana-Farber Cancer Institute, Dana-Farber/Harvard Cancer Center, Massachusetts Institute of Technology, Brigham and Women's Hospital, Memorial Sloan Kettering Cancer Center

Language: English

Topic: Cancer-related Molecular Pathways

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: Dana Farber/ Harvard Cancer Center SPORE in Gastrointestinal Cancer, Mechanisms of Esophageal Carcinogenesis, G4561983161, G5116135637, Integration of early genetic alterations and inflammation in gastroesophageal premalignancy, G6565807268, G8116468226, G8682106772, G9000007884, Cancer Center Support Grant, Integrated Epithelial and Muscosal Biology

OpenAlex ID: W3004751325

FWCI: 3.048

Cites: 99

Cited by: 68

Related to: 10