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When non-coding is not enough

Year: 2020

Type: article

Abstract: A new concept is emerging in the non-coding RNA (ncRNA) field: an increasing number of ncRNAs in fact codify for short peptides that have biological activities. In this issue of JEM, Wang et al. (https://doi.org/10.1084/jem.20190950) report the identification of a long ncRNA (lncRNA)-encoded 60-amino acid polypeptide that they name ASRPS, as well as its ability to inhibit angiogenesis in the deadly triple-negative breast cancer (TNBC).

Source: The Journal of Experimental Medicine

DOI: 10.1084/jem.20192009

Authors: Simone Anfossi, George A. Calin

Institution: The University of Texas MD Anderson Cancer Center

Language: English

Topic: Cancer-related molecular mechanisms research

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W3004788397

FWCI: 0.654

Cites: 15

Cited by: 10

Related to: 10