Work

Absolute Autocatalytic Amplification under Heterogenous Phase Conditions Involving Subsequent Hydride Transfer and a Hemiacetal Intermediate

Year: 2020

Type: article

Abstract: Absolute asymmetric amplification is observed for pyridine alkanol by reaction with iPr 2 Zn vapor under heterogenous conditions. Beside the chiral alkanol, formation of a chiral ester is observed and identified as a subsequent Claisen-Tishchenko product of a hemiacetal intermediate during a Soai absolute amplification.

Source: ChemSystemsChem

DOI: 10.1002/syst.201900060

Authors: Giuseppe Rotunno, Dirk Petersen, Mohamed Amedjkouh

Institution: University of Oslo

Language: English

Topic: Asymmetric Synthesis and Catalysis

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $3,500

Funders: Universitetet i Oslo, Norges Forskningsråd