Biofunctionalization of zirconia with cell-adhesion peptides via polydopamine crosslinking for soft tissue engineering: effects on the biological behaviors of human gingival fibroblasts and oral bacteria
Year: 2020
Type: article
Abstract: , and bacterial adhesion was evaluated by scanning electron microscopy and live/dead staining. PDA and PDA-RGD coatings decreased zirconia surface colonization by both bacterial species to similar extents. Thus, PDA-RGD-functionalized zirconia modulates specific HGF responses, while maintaining the antimicrobial activity of the PDA coating. The selective bio-interaction pattern of this surface modification holds great promise for improving soft-tissue integration around zirconia abutments in clinical applications.
Source: RSC Advances
DOI: 10.1039/c9ra08575k
Authors: Zhen Yang, Mingyue Liu, Yang Yang, Miao Zheng, Yang Yang, Xiaoqiang Liu, Jianguo Tan
Language: English
Subfield: Surfaces, Coatings and Films
Field: Materials Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $1,042
Awards: G6667593423, G7459977468
OpenAlex ID: W3005155715