Biomedical Prevention of Hiv in Women: Challenges and Approaches, With Particular Reference to the Vaginal Microbiome.
Year: 2018
Type: article
Abstract: along with a commensurate increase in the vaginal anaerobes that characterize bacterial vaginosis, strongly increases risk of HIV-1 acquisition and may even modify efficacy of topical tenofovir when used as pre-exposure prophylaxis. bacterial vaginosis, a globally prevalent infection that increases women's risk of HIV-1 acquisition, and presents serious other reproductive health risks and management challenges, presumably involves survival of treatment-resistant biofilm communities. Methods to effect sustained improvement in the vaginal microenvironment are urgently needed.
Source: Europe PMC (PubMed Central)
Author: Jeanne M Marrazzo
Language: English
Subfield: Microbiology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W3006499657