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Engineering primary T cells with chimeric antigen receptors for rewired responses to soluble ligands

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Year: 2020
Type: article
Source: Nature Protocols
DOI: 10.1038/s41596-020-0294-8
Authors: ZeNan L. Chang, Andrew J. Hou, Yvonne Y. Chen
Institutions: University of California, Los Angeles, Washington University in St. Louis, Parker Institute for Cancer Immunotherapy
Language: English

Topic: CAR-T cell therapy research
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, National Institutes of Health, National Heart, Lung, and Blood Institute, NIH Office of the Director, National Cancer Institute, National Institute of General Medical Sciences, National Center for Advancing Translational Sciences
Awards: G1071925744, G2130928551, Engineering robust adoptive T-cell cancer therapy by rewiring TGF-beta signaling, G5177302090, Biotechnology Training in Biomedical Sciences and Engineering, G5450609266, G766868593, Engineering of computational receptors and gene circuits for T-cell immunotherapy, G7809861506, UC BRAID Center for Accelerated Innovation, Cancer Center Support Grant, UCLA Clinical and Translational Science Institute
OpenAlex ID: W3007039663
FWCI: 1.354
Cites: 35
Cited by: 25
Related to: 10
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