Engineering silk materials: From natural spinning to artificial processing
Year: 2020
Type: article
Abstract: Silks spun by the arthropods are "ancient' materials historically utilized for fabricating high-quality textiles. Silks are natural protein-based biomaterials with unique physical and biological properties, including particularly outstanding mechanical properties and biocompatibility. Current goals to produce artificially engineered silks to enable additional applications in biomedical engineering, consumer products, and device fields, have prompted considerable effort towards new silk processing methods using bio-inspired spinning and advanced biopolymer processing. These advances have redefined silk as a promising biomaterial past traditional textile applications and into tissue engineering, drug delivery, and biodegradable medical devices. In this review, we highlight recent progress in understanding natural silk spinning systems, as well as advanced technologies used for processing and engineering silk into a broad range of new functional materials.
Source: Applied Physics Reviews
DOI: 10.1063/1.5091442
Authors: Chengchen Guo, Chunmei Li, Xuan Mu, David L. Kaplan
Institution: Tufts University
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: green
Funders: National Science Foundation, National Institutes of Health, National Eye Institute, National Institute of Allergy and Infectious Diseases, National Institute of Neurological Disorders and Stroke, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of Biomedical Imaging and Bioengineering, National Institute of Dental and Craniofacial Research, Air Force Office of Scientific Research
Awards: G120602424, G1768636052, G1832764922, G1969254292, G2385048669, G3170500465, Models to Predict Protein Biomaterial Performance, Biocomponent Devices: Developing Actuators from Insect Muscles, G5463635937, Degradable orthopedic hardware, G9000005840, G9000009709, G9000022017, G9000043574, G9000056999, G9000060479, Tissue Engineering Resource Center
OpenAlex ID: W3007528079