The Role of Platelets in Ischemic Conditioning.
Year: 2018
Type: article
Abstract: Ischemic heart disease (IHD) is one of the leading causes of death and disability worldwide. Platelets, as the main regulators of hemostasis, are major players in acute myocardial ischemia/reperfusion injury (IRI). Additionally, platelets are modified by endogenous cardioprotective strategies such as ischemic preconditioning, postconditioning, and remote ischemic conditioning. In this article, we provide an overview of the functionional role of platelets in acute myocardial IRI, and highlight their potential as targets for cardioprotection to improve health outcomes in patients with IHD.
Source: PubMed
Institutions: Universidad Nacional Autónoma de México, Benito Juárez Autonomous University of Oaxaca, University of Hawaiʻi at Mānoa, University of Hawaii System, Instituto Tecnológico de Oaxaca, Tecnológico Nacional de México, Justus-Liebig-Universität Gießen, Kazan Federal University, Duke-NUS Medical School, National Heart Centre Singapore, Tecnológico de Monterrey
Language: English
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: green
Funder: National Institutes of Health
OpenAlex ID: W3007553231