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Influence of MRP3 Genetics and Hepatic Expression Ontogeny for Morphine Disposition in Neonatal and Pediatric Patients

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Year: 2020
Type: article
Source: The Journal of Clinical Pharmacology
DOI: 10.1002/jcph.1592
Authors: David Hahn, Tsuyoshi Fukuda, Joshua C. Euteneuer, Tomoyuki Mizuno, Alexander A. Vinks, Senthilkumar Sadhasivam, Chie Emoto
Institutions: Cincinnati Children's Hospital Medical Center, University of Cincinnati, Children's Hospital & Medical Center, University of Nebraska Medical Center, Indiana University Health, Riley Hospital for Children, Indiana University School of Medicine
Language: English

Topic: Pharmacogenetics and Drug Metabolism
Subfield: Pharmacology
Field: Pharmacology, Toxicology and Pharmaceutics
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Center for Advancing Translational Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awards: Pharmacogenetics of Oxycodone, Personalized Care and Persistent Surgical Pain, Center for Clinical and Translational Science and Training, Neonatal PBPK-PD Modeling of Morphine Incorporated with OCT1 Genotype-dependent Developmental Expression, T32 Cincinnati Pediatric Clinical Pharmacology Training Program
OpenAlex ID: W3008549559
FWCI: 2.208
Cites: 27
Cited by: 14
Related to: 10
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