Work

Identification of genes associated with SiHa cell sensitivity to paclitaxel by CRISPR-Cas9 knockout screening.

Year: 2018

Type: article

Abstract: gene family (PPP1R7, PPP2R5B, PPP1R7, and PPP1R11). Importantly, our findings highlighted the newly identified genes that could provide novel insights into the mechanisms of paclitaxel sensitivity in cervical cancer. Cas9 technology provides a reliable method for the exploration of more effective combination chemotherapies for patients at the gene level.

Source: PubMed

Authors: Wei Wei, Yue He, Yu-Mei Wu

Institutions: Capital Medical University, Beijing Obstetrics and Gynecology Hospital

Language: English

Topic: Cancer Treatment and Pharmacology

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3009328565

FWCI: 0.313

Cites: 38

Cited by: 8

Related to: 10