Work

Type I photosensitizers based on phosphindole oxide for photodynamic therapy: apoptosis and autophagy induced by endoplasmic reticulum stress

Year: 2020

Type: article

Abstract: -TPA-PIO-mediated PDT has high potential as a precursor of the immunostimulatory effect for immunotherapy. This work presents a comprehensive protocol for Type I-based purely organic PSs and highlights the significance of considering the working mechanism in the design of PSs for the optimization of cancer treatment protocols.

Source: Chemical Science

DOI: 10.1039/d0sc00785d

Authors: Zeyan Zhuang, Jun Dai, Maoxing Yu, Jianqing Li, Pingchuan Shen, Rong Hu, Xiaoding Lou, Zujin Zhao, Ben Zhong Tang

Institutions: State Key Laboratory of Luminescent Materials and Devices, South China University of Technology, Tongji Hospital, Huazhong University of Science and Technology, China University of Geosciences, Hong Kong University of Science and Technology

Language: English

Topic: Photodynamic Therapy Research Studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: National Natural Science Foundation of China, Natural Science Foundation of Guangdong Province

Awards: G398204835, G5528087338, G6706281528

OpenAlex ID: W3010383348

FWCI: 21.39

Cites: 92

Cited by: 290

Related to: 10