Work

Functional comparison of paper-based immunoassays based on antibodies and engineered binding proteins

Year: 2020

Type: article

Abstract: Binding protein scaffolds, such as rcSso7d, have been investigated for use in diagnostic tests; however, the functional performance of rcSso7d has not yet been studied in comparison to antibodies. Here, we assessed the analyte-binding capabilities of rcSso7d and antibodies on cellulose with samples in buffer and 100% human serum.

Source: The Analyst

DOI: 10.1039/d0an00299b

Authors: Ki-Joo Sung, Yara Jabbour Al Maalouf, Quinlan R. Johns, Eric A. Miller, Hadley D. Sikes

Institutions: Massachusetts Institute of Technology, Singapore-MIT Alliance for Research and Technology

Language: English

Topic: Biosensors and Analytical Detection

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: hybrid