Work

Encephalitozoon cuniculi Genotype III Evinces a Resistance to Albendazole Treatment in both Immunodeficient and Immunocompetent Mice

Year: 2020

Type: article

Abstract: Of four genotypes of Encephalitozoon cuniculi , E. cuniculi genotype II is considered to represent a parasite that occurs in many host species in a latent asymptomatic form, whereas E. cuniculi genotype III seems to be more aggressive, and infections caused by this strain can lead to the death of even immunocompetent hosts. Although albendazole has been considered suitable for treatment of Encephalitozoon species, its failure in control of E. cuniculi genotype III infection has been reported.

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.00058-20

Authors: Bohumil Sak, Klára Brdíčková, Nikola Holubová, Dana Květoňová, Lenka Hlásková, Martin Kváč

Institutions: Institute of Parasitology, Czech Academy of Sciences, Biology Centre, University of South Bohemia in České Budějovice

Language: English

Topic: Parasitic Infections and Diagnostics

Subfield: Parasitology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Grantová Agentura České Republiky