Work

Author response: Chemoptogenetic ablation of neuronal mitochondria in vivo with spatiotemporal precision and controllable severity

Year: 2020

Type: peer-review

Abstract: Novel transgenic zebrafish lines allow selective ablation of neuronal mitochondria by far red light, providing a powerful tool for investigating mitochondrial homeostasis in neurons and mitochondrial mechanisms in neurological disease.

DOI: 10.7554/elife.51845.sa2

Authors: Wenting Xie, Binxuan Jiao, Qing Bai, Vladimir A Ilin, Ming Sun, Charles E Burton, Dmytro Kolodieznyi, Michael J Calderon, Donna B Stolz, Patricia L Opresko, Claudette M St Croix, Simon Watkins, Bennett Van Houten, Marcel P Bruchez, Edward A Burton

Institutions: University of Pittsburgh, Tsinghua University, Carnegie Mellon University, UPMC Health System, UPMC Hillman Cancer Center, Geriatric Research Education and Clinical Center, VA Pittsburgh Healthcare System

Language: English

Topic: Mitochondrial Function and Pathology

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

OpenAlex ID: W3011068368

Cites:

Cited by: 1

Related to: 10