Work

HoxB9 promotes the migration and invasion via TGF-β1/Smad2/Slug signaling pathway in oral squamous cell carcinoma.

Year: 2017

Type: article

Abstract: . Our mechanistic studies suggested that HoxB9 could stimulate the migration and invasion of OSCC cells by targeting EMT via the TGF-β1/Smad2/Slug signaling pathway. Collectively, these findings suggest the vital roles of HoxB9 in OSCC progression through its effects in promoting EMT.

Source: PubMed Central

Authors: Mei Xue, Fei-Ya Zhu, Lin Chen, Kai Wang

Institutions: Peking University, Peking University Third Hospital, Second Xiangya Hospital of Central South University

Language: English

Topic: TGF-β signaling in diseases

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W3011267628

FWCI: 1.229

Cites: 37

Cited by: 18

Related to: 10