Work

NCOA5 deficiency promotes a unique liver protumorigenic microenvironment through p21WAF1/CIP1 overexpression, which is reversed by metformin

Year: 2020

Type: article

Source: Oncogene

DOI: 10.1038/s41388-020-1256-x

Authors: Mark Williams, Xinhui Liu, Yueqi Zhang, Jake Reske, Devika Bahal, Trevor G. Gohl, Daniel Hollern, Elliot Ensink, Matti Kiupel, Rongcheng Luo, Rupali Das, Hua Xiao

Institutions: Michigan State University, Southern Medical University, University of North Carolina at Chapel Hill, UNC Lineberger Comprehensive Cancer Center

Language: English

Topic: Hepatocellular Carcinoma Treatment and Prognosis

Subfield: Hepatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Health and Human Services, National Institutes of Health, National Cancer Institute, National Institute of General Medical Sciences

Awards: A molecular mechanism whereby metformin protects against liver cancer, G1454962509, G3358748259, G3403603663, Integrative Pharmacological Sciences Training Program (IPSTP), G428668243, G5010181840, Role of NCOA5 in hepatic steatosis and hepatocarcinogenesis, G6756703160, G6846834507, G965044247

OpenAlex ID: W3011441982

FWCI: 2.485

Cites: 58

Cited by: 21

Related to: 10