Work

3-Oxo-β-sultam as a Sulfonylating Chemotype for Inhibition of Serine Hydrolases and Activity-Based Protein Profiling

Year: 2020

Type: article

Source: ACS Chemical Biology

DOI: 10.1021/acschembio.0c00090

Authors: Luís A. R. Carvalho, Vanessa T. Almeida, José A. Brito, Kenneth M. Lum, Tânia F. Oliveira, Rita C. Guedes, Lídia M. Gonçalves, Susana D. Lucas, Benjamin F. Cravatt, Margarida Archer, Rui Moreira

Institutions: University of Lisbon, Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Scripps Research Institute

Language: English

Topic: Protease and Inhibitor Mechanisms

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: European Commission, Fundação para a Ciência e a Tecnologia, European Regional Development Fund, National Institute on Drug Abuse, H2020 Research Infrastructures

Awards: G105728699, G1712930557, ActiProbe: Activity-Based Probes as chemical tools for biomarker discovery in Chronic Obstructive Pulmonary Disease, Releasing the full potential of Instruct to expand and consolidate infrastructure services for integrated structural life science research, G3593534703, G3893482033, G4317474242, G496770706, 4612 .: Microbiologia Molecular, Estrutural e Celular, Instituto de Investigação do Medicamento, ONCOLOGIA DE PRECISÃO: TERAPIAS E TECNOLOGIAS INOVADORAS, G5689831786, Releasing the full potential of Instruct to expand and consolidate infrastructure services for integrated structural life science research, SondaDPOC. Sondas baseadas na actividade de proteases para o diagnóstico da Doença Pulmonar Obstrutiva Crónica, 4462 .: iNOVA4Health - Programa de Medicina Translacional (iBET, CEDOC/FCM, IPOLFG e ITQB), G7861799853, G8034029280, G8933067989

OpenAlex ID: W3011688412

FWCI: 0.79

Cites: 30

Cited by: 15

Related to: 10